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What Is Anti-TPO? Causes, Symptoms & High Levels Explained

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  Introduction Anti-TPO (Anti-Thyroid Peroxidase Antibodies) are important markers in the diagnosis of autoimmune thyroid diseases. These antibodies are produced when the immune system mistakenly targets thyroid peroxidase, an enzyme crucial for thyroid hormone production. Elevated Anti-TPO levels are commonly associated with Hashimoto’s thyroiditis and Graves’ disease , both of which impact thyroid function. Testing for Anti-TPO antibodies, along with TSH, Free T4, and Free T3 levels , helps in confirming thyroid disorders, predicting disease progression, and guiding treatment plans. 🔬 What Is Anti-TPO? Thyroid peroxidase (TPO) is an enzyme that helps produce thyroid hormones. When the immune system mistakes this enzyme as harmful, it produces Anti-TPO antibodies. Over time, these antibodies can damage thyroid tissue, leading to inflammation, hormone imbalance, and in some cases, hypothyroidism (underactive thyroid). 📈 Causes of Elevated Anti-TPO Seve...